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Chain Reaction

Chain Reaction is a leading podcast that dives deep into the world of crypto, blockchain, and emerging technologies. Each episode features conversations with top founders, developers, and industry thinkers, breaking down the biggest trends, innovations, and ideas shaping the future of Web3.

Latest episodes

Tristan Thompson Is Still Buying Bitcoin — But He's Betting on These Altcoins Too

From NBA champion to crypto investor, Tristan Thompson reveals his biggest bets, meme coin trades, and personal investment strategy. In this exclusive Cointelegraph interview, Thompson discusses his biggest altcoin wins and losses, why he continues buying Bitcoin, his experience trading meme coins…

10mOct 22, 2026

ADA Is Down. What Is Cardano Actually Building?

You bought a tokenized stock. But did you buy the same rights as a shareholder?

6mOct 20, 2026

Why Yat Siu Believes Altcoins Could Outperform Bitcoin

Animoca Brands Chairman Yat Siu joins Cointelegraph at TOKEN2049 to discuss the future of AI agents, crypto trading, and digital privacy. Could AI agents eventually handle most crypto trades? What happens when AI platforms know your most personal information, or suddenly revoke access to your…

17mOct 14, 2026

Crypto Has 2 Years to Prove Itself. What Happens Next? - Justin Sun

Crypto has two years to prove itself. What happens if it doesn’t?

4mOct 12, 2026

Chain Reaction with Bitpanda CEO Christian Trummer

Cointelegraph’s Ciaran Lyons sits down with Bitpanda CEO Christian Trummer to discuss how MiCA has pushed many crypto companies out of the market and whether that has strengthened retail investors’ confidence in regulated players.

25mOct 2, 2026

Chain Reaction with Bitget CEO Gracy Chen

Cointelegraph’s Ciaran Lyons sits down with Bitget CEO Gracy Chen to discuss the crypto exchange’s recent $388 million hack, including why she believes it was linked to North Korea and the tough questions over whether it could have been an inside job.

26mSep 29, 2026

Chain Reaction with GenLayer's Albert Castellana

Cointelegraph’s Ciaran Lyons sits down with GenLayer co-founder Albert Castellana to discuss his bold prediction that humans will have no role in crypto trading by 2031.

29mSep 25, 2026

Chain Reaction with Coin Bureau's Nic Puckrin

Cointelegraph’s Ciaran Lyons sits down with Coin Bureau founder Nic Puckrin to discuss how the crypto industry might look today if Donald Trump had never been elected president, and whether the industry would be in a better or worse position under an alternative administration.

28mSep 23, 2026

Chain Reaction with Himanshu Sahay

Cointelegraph's Ciaran Lyons speaks with Arch Lending co-founder Himanshu Sahay about which tokens are drawing the most interest in crypto lending, and how lending firms have strengthened their risk safeguards in the years since Celsius collapsed.

25mSep 23, 2026

Chain Reaction with Solstice CEO Ben Nadareski

Cointelegraph's Ciaran Lyons sits down with Solstice CEO Ben Nadareski to discuss why Solana's reputation as the memecoin capital of crypto may not be a bad thing, why he is bullish on the broader Solana ecosystem and his case for SOL reaching $1,000 by 2030.

26mSep 21, 2026

Chain Reaction with CoinShares' Luke Nolan

Cointelegraph's Ciaran Lyons sits down with CoinShares crypto researcher Luke Nolan to discuss the impact of the US Federal Reserve's recent interest rate increase on crypto markets, Germany's surprising progress in crypto adoption and why the UK appears to be falling behind.

27mSep 17, 2026

Chain Reaction with The Daily Wolf's Scott Melker

Cointelegraph’s Ciaran Lyons sits down with Scott Melker to discuss the US CLARITY Act stalling this week, what a potential interest rate hike could mean for crypto, and the crypto narratives Melker is most excited about heading into 2026.

28mSep 16, 2026

Chain Reaction US CLARITY Act bonus episode with 1inch and Fireblocks

Cointelegraph’s Ciaran Lyons sits down with 1inch Chief Legal Officer Orest Gavryliak and Fireblocks US Policy Director Jessica Martinez for a special episode of CHAIN REACTION to discuss the US CLARITY Act ahead of today’s vote, where the bill needs 60 votes to progress.

27mSep 15, 2026

Chain Reaction with Phemex CEO Federico Variola

Cointelegraph’s Ciaran Lyons sits down with Phemex CEO Federico Variola to discuss this week’s US CLARITY Act vote and why humans will always have a role in crypto trading, even as AI agents become more capable of handling trades.

26mSep 15, 2026

Chain Reaction with Injective Labs' John Medel

Cointelegraph’s Ciaran Lyons sits down with Injective Labs Head of Policy John Medel as the final vote on the US CLARITY Act approaches this week. Medel shares why he is bullish on the outcome and what the legislation could mean for the US crypto industry in the near term.

25mSep 14, 2026

Chain Reaction with Crypto Banter's Ran Neuner

Cointelegraph’s Ciaran Lyons sits down with Crypto Banter founder Ran Neuner to discuss Hyperliquid’s “biggest issue,” the launch and collapse of Hunter Biden’s memecoin and whether celebrity tokens can ever succeed.

30mSep 11, 2026

Chain Reaction with crypto entrepreneur Lark Davis

Cointelegraph’s Ciaran Lyons sits down with crypto entrepreneur Lark Davis to discuss his bullish outlook for real-world assets and tokenization, why influencers are increasingly jumping between crypto and AI depending on what’s generating the most excitement, and his broader outlook for the…

29mSep 10, 2026

Chain Reaction with Efe Kelemci aka "Crypto Kid"

Cointelegraph's Ciaran Lyons sits down with Efe Kelemci, aka "Crypto Kid," to discuss why Bitcoin is "easily" a better bet than gold, where he sees Bitcoin's price heading, and whether the bear market is finally behind us.

29mSep 9, 2026

Chain Reaction with Silicon Valley star T.J. Miller

Cointelegraph's Ciaran Lyons sits down with Silicon Valley star T.J. Miller to discuss Bitcoin adoption among Hollywood celebrities and why education is key to bringing more people into Bitcoin.

35mSep 9, 2026

Chain Reaction with MidChains CEO Basil Al Askari

Cointelegraph's Ciaran Lyons sits down with MidChains CEO Basil Al Askari to discuss how tokenization could transform the world, whether Bitcoin is edging closer to a bull or bear market, and the broader outlook for crypto.

27mSep 7, 2026

Chain Reaction with "Miss Teen Crypto" Randi Hipper

Cointelegraph's Ciaran Lyons sits down with "Miss Teen Crypto" Randi Hipper to discuss Bitcoin's price outlook, the US CLARITY Act, broader crypto adoption and more.

28mSep 4, 2026

Chain Reaction with RedStone founder Marcin Kazmierczak

Cointelegraph’s Ciaran Lyons sits down with RedStone founder Marcin Kazmierczak to discuss the tokenization of real-world assets and why the momentum behind the industry is unlikely to be stopped, regardless of whether regulations work in its favour.

25mSep 3, 2026

Chain Reaction with Moon Show Host Carl Moon

Will retail investors ever come back to crypto? The Moon Show host Carl Moon believes that Bitcoin will need to reach new all-time highs first.

28mSep 2, 2026

Chain Reaction with Swan Bitcoin CEO Cory Klippsten

Would Bitcoin’s price be higher or lower if spot Bitcoin ETFs had never launched in 2024? Swan Bitcoin CEO Cory Klippsten explains why he believes Bitcoin would actually be trading higher today without them.

23mSep 1, 2026